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mdck wt cell line  (ATCC)


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    Structured Review

    ATCC mdck wt cell line
    <t>MDCK</t> permeability assay results for selected compounds (A–C) Efflux ratios are shown for the <t>(A)</t> <t>MDCK-WT,</t> (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).
    Mdck Wt Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 6879 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mdck wt cell line/product/ATCC
    Average 99 stars, based on 6879 article reviews
    mdck wt cell line - by Bioz Stars, 2026-05
    99/100 stars

    Images

    1) Product Images from "Repurposing drugs for treating the neurobehavioral manifestations of PTEN hamartoma tumor syndrome"

    Article Title: Repurposing drugs for treating the neurobehavioral manifestations of PTEN hamartoma tumor syndrome

    Journal: iScience

    doi: 10.1016/j.isci.2026.115428

    MDCK permeability assay results for selected compounds (A–C) Efflux ratios are shown for the (A) MDCK-WT, (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).
    Figure Legend Snippet: MDCK permeability assay results for selected compounds (A–C) Efflux ratios are shown for the (A) MDCK-WT, (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).

    Techniques Used: Permeability



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    <t>MDCK</t> permeability assay results for selected compounds (A–C) Efflux ratios are shown for the <t>(A)</t> <t>MDCK-WT,</t> (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).
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    <t>MDCK</t> permeability assay results for selected compounds (A–C) Efflux ratios are shown for the <t>(A)</t> <t>MDCK-WT,</t> (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).
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    Image Search Results


    MDCK permeability assay results for selected compounds (A–C) Efflux ratios are shown for the (A) MDCK-WT, (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).

    Journal: iScience

    Article Title: Repurposing drugs for treating the neurobehavioral manifestations of PTEN hamartoma tumor syndrome

    doi: 10.1016/j.isci.2026.115428

    Figure Lengend Snippet: MDCK permeability assay results for selected compounds (A–C) Efflux ratios are shown for the (A) MDCK-WT, (B) MDCK-MDR1, and (C) MDCK-BCRP assays. The dotted line marks the favorable efflux ratio <2. Favorable values are highlighted in green, unfavorable ratios in purple. Note that dactolisib shows a moderate to good efflux ratio in all three assays; however, generally a poor permeability (see ).

    Article Snippet: The MDCK WT cell line was obtained from ATCC (CRTL-2936) and grown in DMEM (Dulbecco’s Modified Eagle Medium, GlutaMAX) with 10% heat inactivated fetal bovine serum (HI FBS), at 37°C and 5% CO2.

    Techniques: Permeability